منابع مشابه
CD105 (endoglin), apoptosis, and stroke.
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متن کاملEndoglin (CD105) and microvessel density in oral squamous cell carcinoma.
Recent studies revealed that CD105 is intensively expressed in tumor vasculature, and may be an important prognostic indicator for the outcome in a number of malignancies. The aim of our study was to evaluate the CD105 expression and microvessel density in oral squamous cell carcinoma (OSCC). Nineteen surgical specimens with OSCC were immunohistochemical analyzed with CD105 (Endoglin). We deter...
متن کاملEndoglin deficiency impairs stroke recovery.
BACKGROUND AND PURPOSE Endoglin deficiency causes hereditary hemorrhagic telangiectasia-1 and impairs myocardial repair. Pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia-1 are associated with a high incidence of paradoxical embolism in the cerebral circulation and ischemic brain injury. We hypothesized that endoglin deficiency impairs stroke recovery....
متن کاملExpression of endoglin (CD105) and endothelial nitric oxide synthase in head and neck arteriovenous malformations.
IMPORTANCE Endoglin (CD105) and endothelial nitric oxide synthase (eNOS) assist in regulating vascular development. Variation in expression of these factors is linked to errors in vascular growth and remodeling in invasive lesions. OBJECTIVE To clarify the role of endoglin and eNOS in the growth of extracranial head and neck arteriovenous malformations (AVMs), an invasive and high-flow vascul...
متن کاملENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours
ENDOGLIN/CD105 (ENG) is a transmembrane glycoprotein and an auxiliary unit of the transforming growth factor-β (TGF-β); receptor, expressed predominantly in vascular endothelium. Noteworthy, Eng mRNA expression has been reported also in Kit(+) interstitial cells of Cajal (ICC) in the mouse intestine. Gastrointestinal stromal tumours (GIST) are thought to derive from ICC. Here we have investiga...
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ژورنال
عنوان ژورنال: Stroke
سال: 2004
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000125309.37971.82